자가골 블록 이식을 이용한 수평골 증강술시 이식골의 치유
The histologic study of bone healing after horizontal ridge augmentation using auto block bone graft
오재권, 이백수, 최병준,
소속 상세정보
오재권 ( Oh Jae-Kwen ) - 경희대학교 치의학전문대학원 구강악안면외과학교실
이백수 ( Lee Baek-Soo ) - 경희대학교 치의학전문대학원 구강악안면외과학교실
최병준 ( Choi Byung-Jun ) - 경희대학교 치의학전문대학원 구강악안면외과학교실
KMID : 0360120090310030207
Abstract
Purpose: The aim of the present study is to evaluate the long term bone healing after horizontal ridge augmentation using auto block bone graft for implant installation timing.
Materials and Methods: Five Beagle dogs(which were 14 months old and weighted approximately 10kg). In surgery 1(extraction & bone defect), premolars(P2, P3,P4) were extracted and the buccal bone plate was removed to create a horizontally defected ridge. After three months healing, in surgery 2(ridge augmentation). Auto block bone grafts from the mandibular ramus were used in filling the bone defects were fixed with stabilizing screws. The following fluorochrome labels were given intravenously to the beagle dogs: oxytetracycline 1week after the surgery, alizarin red 4 weeks after the surgery, calcein blue 8 weeks after the surgery . The tissue samples were obtained from the sacrificed dogs of 1, 4, 8, 12, 16 weeks after the surgery. Non-decalcified sections were prepared by resin embedding and microsection to find thickness of 10micro for the histologic examination and analysis.
Results:1. We could achieve the successful reconstruction of the horizontal bone defect by auto block bone graft. The grafted bone block remained stable morohologically after 16 weeks of the surgery. 2. In the histologic view. We observed osteoid tissue from the sample 4th week sample and active capillary reconstruction in the grafted bone from the 12th week sample. Healing procedures of auto bone grafts were compared to that of the host bone. 3. Bone mineralization could be detected from the 8th week sample. 4. Fluorochrome labeling showed active bony changes and formation at the interface of the host bone and the block graft mainly. Bony activation in the grafted bone could be seen from the 4th week samples.
Conclusions: Active bone formation and remodeling between the grafted bone and host bone can be seen through the revascularization. After the perfect adhesion to host bone, Timing of successful implant installation can be detected through the ideal ridge formation by horizontal ridge augmentation
키워드
Auto block bone;Horizontal bone augmentation;Bone Labeling
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